From Zurich Gotthard, Milan, Bologna, Florence, Paganico (approx. 7.5 hours)
From Bern Great Saint Bernard, Aosta, Genoa, La Spezia, Grosseto, Paganico (approx. 8 hours)
From Munich Innsbruck, Brenner, Verona, Modena, Bologna, Florence, Paganico (approx. 8.5 hours)
From Rome Civitavecchia, Grosseto, Paganico (approx. 2.5 hours)